Planning has always been an essential part of scientific and practical activities, driven by the need for purposeful development in science, technology and society.The paper focuses on the study of the development of planning in the context of the history of economics and economic thought.The purpose of the paper is to study the formation of planni
Nucleosomes restrict the occupancy of most transcription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs have high affinities to nucleosome-embedded sites and facilitate nucleosome displacement.To understand this process mechanistically, we investigated two Saccharomyces cerevisiae TFs, Reb1 and Cbf1.We sh
Carriers of highly leukotoxic genotypes of Aggregatibacter actinomycetemcomitans are at high risk for rapid degradation of tooth-supporting tissues.The leukotoxin (LtxA) expressed by this bacterium induces a rapid pro-inflammatory response in leukocytes that results in cell death.The aim of the present study was to increase the understanding of Ltx
In an era marked by increasing demands for stability and durability in construction, the importance of damage detection in concrete structures cannot be overstated.As these structures underpin the safety and longevity of vital assets, this paper embarks on a comprehensive exploration of methodologies to enhance precision and reliability in 2D concr
For many deaf signers, a signed language is their first or preferred language; spoken or written languages are often second languages and literacy levels among deaf signers vary.Historically, surveys carried out with deaf signers have been in written form, which means that findings of such studies may be problematic in terms of whether participants